一场惨绝人寰的连环惨案，让雷杰米一直被恶灵缠身困扰。但只有他知道真正的凶手是一种“看不见、摸不着”的在阴影中潜伏的恶灵：无声逼近、瞬间夺命，只留破碎尸体与无法解释的诡异痕迹。 雷杰米与女医生卢娜联合调查时发现，一切源于他童年母亲死亡有关的研究秘密释放的远古恶灵，它正以扭曲低语和血迹标记猎物，吞噬猎物的恐惧，将他们逐个拖入绝望死亡。证人离奇发狂、无人医院深处传来湿滑爬行声……而每当人心恐惧到极点， 恶灵便会在黑暗中悄悄靠近…… 身边人接连惨死，雷杰米必须直面纠缠他一生的“恶灵”，才能拯救他所爱之人。当他们以为噩梦终结时，恶灵却失控逃逸扩散，更大的恐惧才刚刚苏醒……
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